Last night, Jamie Dimon, the chief executive of banking giant JPMorgan JPMorgan, informed staff that he is currently being handled for throat cancer. In a memo, he explained that he would commence eight weeks of chemotherapy and radiation therapy at Memorial Sloan Kettering Cancer Center.
He wrote:
The excellent news is that the prognosis from my medical doctors is excellent, the cancer was caught quickly, and my problem is curable. Following thorough exams that included a CAT scan, PET scan and a biopsy, the cancer is confined to the authentic internet site and the adjacent lymph nodes on the correct side of my neck. Importantly, there is no evidence of cancer elsewhere in my entire body.
It is not possible to speculate on Dimon’s cancer beyond what he put in his memo. I contacted JPMorgan and the organization could not verify any other specifics about his conditions. But it is really possible that Dimon has been swept up, along with 1000′s of other guys, by an more and more typical illness: throat cancer caused by infection with the human papilloma virus, or HPV.
“It wouldn’t be uncommon,” says Eric Genden, chief of head and neck oncology at the Mount Sinai Hospital in New York. “This is an epidemic.”
In 2008, the last year for which information are accessible, the Centers for Disease Control & Prevention estimate that 2,370 girls and 9,356 males created HPV-triggered head and neck cancer, about a third of the cases of head and neck cancer that 12 months.
HPV surpassed other triggers of throat cancer in 2004.
But Genden says that 70% to 90% of head and neck cancer circumstances worldwide are now triggered by HPV the American Cancer Society American Cancer Society estimates that this yr, there will be 42,440 instances of head and neck cancer in the U.S.
Traditionally, head and neck cancer individuals have been older guys who smoke and drank heavily. The alcohol and tobacco broken the cells in the throat, eventually foremost to cancer.
HPV-brought on cancer is different. The guys (and it’s nevertheless mostly men) who get it are younger. In a series of instances at Mount Sinai, they had been between 35 and 65.
Five years in the past, I profiled Maura Gillison, the Ohio State University researcher who aided establish that this was a massive problem. She advised me how when enrolling a research numerous many years ago, she’d recruited, in sequence, a malpractice lawyer, doctor, a scientist and a rear admiral. The very first patient I spoke to about his HPV throat cancer was a consultant and economist who later on died from his illness. Two years in the past, I wrote about a 50-year-outdated biotech CEO who also had HPV throat cancer. Final yr, the actor Michael Douglas explained that his throat cancer was brought on by HPV.
The level is that these are men a lot like Dimon: CEOs and consultants, males at the peak of their lives and professional electrical power. And their numbers are escalating.
The chart over demonstrates the total variety of throat cancer situations, and also the volume triggered by HPV and the volume that weren’t, amongst individuals in Hawaii, Iowa, and Los Angeles. As you can see, in 2004 the HPV cancers began to outnumber the type triggered by smoking and consuming.
How do you get HPV cancer? HPV is sexually transmitted. It’s mostly acknowledged as a trigger of cervical cancer, which is what occurs when it infects women. But males can get it by doing cunnilingus. It is also feasible, even though less most likely, that it can be transmitted by kissing. Eighty % of sexually active men and women in between the ages of 14 and 44 have had oral intercourse with an opposite intercourse partner. Researchers estimate that HPV throat cancer in guys will be more typical than cervical cancer in women in the U.S.
Most strains of HPV do not cause cancer, either in the throat or the cervix. And most HPV infections are cleared by the physique. But in a minority of situations, possibly ten%, they persist. If the strain is of the proper selection – for instance, the HPV sixteen strain of the virus – this infection can ultimately lead to cancer. When it comes to throat cancer, this process takes decades.
The good information is that throat cancer caused by HPV is far less deadly than the outdated kind that resulted from persistent tobacco use and drinking. Some researchers have cited information that it is 80% curable. In a series of 500 individuals who were early in their illness conducting at Sinai, much more than 90% were still cancer free 5 many years after surgery. And in that examine Sinai was deliberately employing significantly less invasive surgical procedure and skipping chemotherapy and radiation in the interest of sparing guys side results.
A single hope is that the vaccines designed to avert HPV infection in girls – Gardasil, from Merck Merck, and Cervarix, from GlaxoSmithKline GlaxoSmithKline – could avoid HPV infection in the throat and, consequently, cancer later on. But there’s no way to show this. Drug organizations funded studies showing the vaccines prevented the formation of precancerous lesions in the cervix, but there is no way to do some thing similar in the throat.
“I feel the downside of possessing the HPV vaccine in youthful boys is so reduced and the prospective upside is so high that I advocate it,” says Genden. “Do we have evidence that it prevents oropharangeal cancer in boys? No.”
Why Thousands Of Men Like JPMorgan CEO Jamie Dimon Are Acquiring Throat Cancer
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