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20 Ekim 2016 Perşembe

Gay men are battling a demon more powerful than HIV – and it’s hidden| Owen Jones

It had been three years since I’d met up with my first boyfriend – let’s call him Steven. When he walked into a Brixton pub in June, it was a shock. I’d first met him well over a decade ago, and back then he was sporty, a bit of a health freak: other than the usual occasional student alcohol binge, relatively strait-laced. This Steven had dilated pupils, red marks on his arms, and his head jerked erratically as he spoke manically. He was addicted to crystal meth, and had an abusive relationship with other drugs and alcohol.


Steven’s story is all too revealing about a silent health crisis afflicting gay men. The words “health crisis” in conjunction with “gay men” normally conjures up the HIV catastrophe that decimated the gay and bisexual community in the 1980s. In the developed world, HIV is no longer the death sentence it once was, although the treatment can cause health complications, and in the UK an estimated 6,500 men who have sex with men live with undiagnosed infections. A far greater menace is mental distress – impossible to disentangle from a society riddled with homophobia – and the drug and alcohol abuse that can follow.


Steven has been clean for 66 days, has enthusiastically taken to treatment and volunteers at his local support group. But why – like so many gay men – did he succumb to addiction? When Steven came out, at the age of 15 years old, his parents drove him to a pseudo-clinic run by fundamentalist Christians to be cured of his homosexuality. But he doesn’t speak with bitterness. “I know they love me and they were doing the best they could,” he says. “They didn’t know what I needed, so they looked to their own experience, a culture that taught that if you were gay it was a disaster. You’d be lonely, you’d get Aids, you’d find life difficult. They felt they were trying to support me.”


The problem was far broader than his family, though. Coming out as a teenager in the early 00s meant almost inevitable bullying at school, a lack of awareness of where to find positive role models, and homophobic voices amplified by the media. “Taken together, it meant I was isolated and thought that I was the problem.” Internalising that shame at such a young age inflicts long-term damage – and explains much of his current turmoil.


It’s an issue covered by the former Attitude editor Matthew Todd in his utterly brilliant – and disturbing – recent book Straight Jacket. He identifies a number of problems that most gay men, if they were honest, would at least recognise: “Disproportionately high levels of depression, self-harm and suicide; not uncommon problems with emotional intimacy … and now a small but significant subculture of men who are using, some injecting, seriously dangerous drugs, which despite accusations of hysteria from the gatekeepers of the gay PR machine, are killing too many people.” He lists a disturbing number of gay friends, acquaintances and people in the public eye who struggled with addictions and took their own lives.


The statistics are indeed alarming. According to Stonewall research in 2014, 52% of young LGBT people report they have, at some point, self-harmed; a staggering 44% have considered suicide; and 42% have sought medical help for mental distress. Alcohol and drug abuse are often damaging forms of self-medication to deal with this underlying distress. A recent study by the LGBT Foundation found that drug use among LGB people is seven times higher than the general population, binge drinking is twice as common among gay and bisexual men, and substance dependency is significantly higher.


Why? As Todd puts it: “It is a shame with which we were saddled as children, to which we continue to be culturally subjected.” The problem gay people have isn’t their sexuality, but rather society’s attitude to it. It is “our experience of growing up in a society that still does not fully accept that people can be anything other than heterosexual and cisgendered [born into the physical gender you feel you are]”. There’s the weight of centuries of hatred and bigotry, with legally enforced discrimination only dismantled in very recent times. All gay and bisexual men – as well as women and trans people – grow up hearing homophobic and transphobic abuse. “Gay” is a word used in the playground as the repository for all that is bad. Popular films and TV programmes have largely lacked sympathetic, well-rounded LGBT characters, often resorting to crude homophobic tropes. Even the inability to hold hands with someone you love in almost any public space is a reminder that a depressingly large chunk of the population still rejects you. Coming out – a process that isn’t a one-off, but a wearingly repetitive event in different contexts – involves constant stress. And for those who think it’s all inevitably getting better, since the EU referendum, there’s been a 147% rise in homophobic hate crimes.


Society has damaged – and continues to damage – LGBT people. That’s not to overstate the case (and focusing on my experience as a gay man): being gay does not mean being in a state of misery. As Todd puts it, there are lots of contented, successful gay people, and progress in recent times has been astonishing, including equal marriage. Coming out is like coming up for air for the vast majority of LGBT people: the alternative is so much more miserable. But this is a health crisis that is not spoken about enough: the toxic combination of mental distress, drugs and alcohol abuse.


It is a crisis that is not being dealt with. Despite the government’s promises to grant mental and physical health parity of esteem, last year Mind reported an 8% real terms drop in mental health services funding since 2010. Cuts, according to health thinktank the King’s Fund, have contributed to “widespread evidence of poor-quality care”. Many LGBT services in particular have been devastated: as the TUC pointed out in 2014, they were “already coping on a shoestring. Some have faced drops in up to 50%.”


Because of our internalised shame, LGBT people often find it difficult to talk about the problems we collectively face. The danger is always of reinforcing the damaging stereotypes that have already caused so much distress. But we have to confront a crisis that is damaging health and taking people’s lives. Society has to take responsibility, too: it is its continued refusal to treat LGBT people as equals that is causing so much pain. If Theresa May’s government really does want to prove it isn’t just a pound-shop Ukip tribute band, perhaps it should take this issue seriously and review David Cameron’s cuts. The lives of LGBT people depend on it.


In the UK, the Samaritans can be contacted on 116 123. In the US, the National Suicide Prevention Hotline is 1-800-273-8255. In Australia, the crisis support service Lifeline is on 13 11 14. Hotlines in other countries can be found here



Gay men are battling a demon more powerful than HIV – and it’s hidden| Owen Jones

27 Şubat 2014 Perşembe

Can David Nutt wean us off the demon drink with his alcohol substitute? | Neil Brady

Cancer incidence is set to enhance by 70% globally in between now and 2024, according to the Globe Health Organisation’s Planet Cancer Report published earlier this month. The report states that considerably of the enhance will be down to life style variables – not just smoking, but also bodily inactivity and extreme consumption of sugar (foremost to obesity) and alcohol.


Shifting people’s behaviour is notoriously difficult and costly, but what if it had been attainable to tremendously lessen the toxic effect of 1 of these lifestyle alternatives, alcohol? This is what David Nutt, professor of neuropsychopharmacology at Imperial School London and former chairman of the United kingdom government’s Advisory Council on the Misuse of Medicines hopes to achieve with an alcohol substitute he is working on. The drug would be intoxicating but harmless.


I spoke to Nutt last week about the genesis of his alcohol substitute. “I have spent 20 years making an attempt to decrease the harms of alcohol, and then about 10 years ago – even though operating under the UK’s Foresight initiative – we thought ‘we’ll never ever end alcohol becoming toxic because it really is intrinsically such. It triggers cancer or liver condition, for instance. So why don’t we exchange it with a safe drug?’”


His proposed substitute to alcohol operates by targeting the very same receptors as the neurotransmitter gamma aminobutyric acid, or Gaba, which has a “comforting” result on the central nervous method. These receptors are the target of numerous extensively employed medication, which includes barbiturates, benzodiazepines (such as Valium) – and alcohol.


Nutt’s alcohol substitute is a benzodiazepine derivative, but he is adamant that what he is providing is a lot more than just one more kind of Valium. It targets the same websites in the brain, but he believes the drug will not lead to the identical problems with addiction and withdrawal. “Modern science enables us to target the comforting and intoxicating part, although steering clear of the undesirable parts like addiction and withdrawal,” he explained.


The drug is currently employed in humans for other indications, he adds. “Addiction is a complex procedure. I am assured that the physically addictive properties of this drug are minimum, and that it is a lot less addictive than alcohol. Far more operate will be necessary just before I can conclusively show this, nevertheless.”


For industrial factors, he is not prepared to reveal the drug’s identity for the time getting. But in its present type, it has some crucial limitations. In distinct, it cannot be used in beer or wine due to the fact if affects their flavour, and tweaking the drug’s chemistry to make it much more palatable will need “much more funding, a lot more chemistry muscle”, acknowledges Nutt.


In the meantime, he plans to provide it in the type of a non-alcoholic cocktail. The intoxicating result of the initial three “doses” will be cumulative, he stated, but subsequent shots will have no effect. Remarkably, he has also developed an antidote, or “sober-up pill”.


I asked him what industry he had in mind for his alcohol substitute. Who would buy it?


“I want it to be offered in higher-top quality cocktail bars where folks go and re-understand about the pleasures of drinking in a social surroundings with buddies, consuming sensible amounts,” he said. “Possibly it could be sold alongside alcohol, so that men and women could see the big difference in between it and individuals consuming alcohol and getting into fights.


“It will be an upmarket merchandise for people who want to drink responsibly. You can never ever do that with alcohol since it turns off the parts of the brain that create duty.”


Nutt admitted that individuals are often sceptical when they hear about his perform, but he believes the harms of alcohol demand radical alternatives.


“Alcohol is the foremost result in of death in Britain nowadays in guys in between the ages of sixteen and 50,” he stated. “It has overtaken traffic accidents, suicide and cancer. The overall health fees amount to £3bn a 12 months. Most folks say, ‘my God, what a clever idea, but it could never work. How are you going to license it? Is it going to be a legal higher?’


“At a single degree they’re proper,” explained Nutt. “Alcohol is a drug that has been all around for thousands of years, and western society is immersed in it, so this will be really a revolution.”


The response of drinks firms therefore far has ranged from baffled to sympathetic. One particular of the world’s greatest, Diageo, was sceptical.


“Diageo does not believe a synthetic kind of alcohol that decreases or eliminates the harmful effects of extreme use is on the horizon,” a spokesperson for the firm informed me. “Based on our comprehending, Dr Nutt is seeking to generate a derivative of benzodiazepine. Our business has some of the world’s most iconic brand names, many with hundreds of years of tradition and craft. Buyers about the globe take pleasure in our manufacturers responsibly and we believe they are hunting for the craft and taste associated with our brand names and will carry on to do so.”


Sarah Williams, overall health information officer with Cancer Study Uk, was much less dismissive, describing the alcohol substitute as “an interesting thought”, noting that “the much less alcohol a person drinks, the decrease their chance of cancer”. But she explained more study into Nutt’s drug would be essential.


“We’re keen to see how the analysis develops, particularly to verify that it doesn’t result in a various set of well being hazards. But it’s crucial that this doesn’t distract policymakers from other evidence-based mostly techniques to protect public overall health by decreasing alcohol consumption in the Uk, such as minimum unit pricing.”


Prof Nutt is adamant that the drug is risk-free, and that just as the tobacco business at some point came to accept the worth of electronic cigarettes, the alcohol market will come to accept that an alcohol substitute has a location.


He is presently working with Imperial Innovations, a technological innovation commercialisation business that collaborates with 4 of the UK’s leading universities, to deliver the drug to marketplace. With enough funding, he thinks this could come about as soon as subsequent yr.


“I know the product is secure. And the drinks organizations know that their item kills [almost] 3 million individuals a yr. They would like a safer alcohol, but the industry is expanding in Asia and Africa. That is why we need to have to incentivise them to modify. What we require is for the public to say ‘we need this’, and for governments to inspire it as a well being substitute.”



Can David Nutt wean us off the demon drink with his alcohol substitute? | Neil Brady