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1 Ocak 2017 Pazar

London ambulance staff log calls with pen and paper after IT failure

Staff at one of the country’s biggest ambulance services had to log emergency calls manually overnight because of technical issues in the control room, delaying response times.


It is understood London ambulance service’s computer system crashed, forcing staff to record details of calls by pen and paper for nearly five hours on one of the busiest nights of the year.


A spokeswoman said staff were trained to deal with such situations and were able to prioritise responses to those in greatest need.


The deputy director of operations Peter McKenna said: “Due to technical difficulties, our control room was logging emergency calls by pen and paper from 12.30am to 5.15am.


“Our control room staff are trained to operate in this way and continue to prioritise our response to patients with life-threatening conditions, using the same triage system as usual.


“We also have additional clinicians on duty to offer control room staff clinical advice if it is needed.”



London ambulance staff log calls with pen and paper after IT failure

15 Mayıs 2014 Perşembe

Statins might have no harmful side results, as controversial paper withdrawn

Creating in today’s edition of the BMJ, editor-in-chief Dr Fiona Godlee said it wanted to alert readers, the media, and the public to the withdrawal of the statements “so that sufferers who could advantage from statins are not wrongly deterred from starting or continuing treatment simply because of exaggerated worries over side results”.


She added that their withdrawal raised the query of whether the total articles should be pulled, saying: “Nonetheless, as the editor accountable for publishing the articles or blog posts, I have a vested interest in not retracting them unless of course the situation of performing so is entirely clear.


“So I have decided the right point to do is to pass this choice to an independent panel.”


She extra: “Meanwhile, the BMJ will proceed to debate the important questions raised in the two these articles: whether the use of statins ought to be extended to a vastly wider population of folks at minimal threat of cardiovascular disease and the role of saturated fat in heart ailment.”


Statins are at the moment provided to as several as seven million individuals in the United kingdom who have a 20 per cent danger of establishing cardiovascular condition inside of 10 years.


The National Institute for Overall health and Care Excellence (Nice) known as for the NHS to widen this to cover people with just a ten per cent chance following a examine by Professor Rory Collins and a staff at Oxford University.


Prof Collins criticised the papers by Dr Abramson and Dr Malhotra in March, saying they were misleading. It was he who requested the papers be withdrawn, the BMJ explained.


The independent panel will be chaired by Iona Heath, a former chairwoman of the Royal College of General Practitioners and a member of the BMJ’s ethics committee.


The journal mentioned tips from the Global Committee on Publication Ethics state that journals need to contemplate retracting a publication if there is “clear evidence that the findings are unreliable, either as a consequence of misconduct or sincere error”.


The BMJ explained Dr Abramson’s paper re-analysed information from the Cholesterol Treatment method Trialists’ (CTT) Collaboration which showed treating individuals with a less than 20 per cent danger of heart ailment with statins made no distinction to the death fee in excess of the following 10 many years.


This finding has not been challenged, but the paper also cited information from a separate “uncontrolled observational study” and “incorrectly concluded” that statin side-effects occur in 18-20 per cent of patients.


The identical blunder was manufactured by Dr Malhotra in the identical edition of the BMJ and it is these statements that have been withdrawn, the journal said.


Dr Godlee added: “The BMJ and the authors of each these articles have now been produced mindful that this figure is incorrect, and corrections have been published withdrawing these statements.”


Statins are a group of medicines that assist reduce rates of lower-density lipoprotein (LDL) cholesterol – so called “negative cholesterol” – in the blood.


Higher-rates of LDL cholesterol are linked to hardening and narrowing of the arteries, which can lead to heart condition, heart attacks and stroke.


Individuals can reduce their danger naturally by consuming a healthier diet plan, reduced in saturated fats, and growing the amount of omega three fatty acids in their diet.


Cardiovascular ailment is the leading lead to of death in England and Wales. In 2010, 1 in 3 folks died from it.


The NHS estimates that statins save 7,000 lives a 12 months in the United kingdom.



Statins might have no harmful side results, as controversial paper withdrawn

13 Nisan 2014 Pazar

Are we utilizing antidepressants to paper more than the cracks of a fractured society?

The probabilities are that you know someone who takes antidepressants. Or possibly you take them your self. If so, you are in very good firm. Far more than 50m prescriptions for antidepressants are written in the Uk every 12 months and, despite the fact that the not all of the capsules will be swallowed – taking into account repeat prescriptions and failure to collect from pharmacies – the figure is still staggeringly high.


There is a constructive side to the 50m statistic, although. It suggests that as the stigma has decreased, folks have become more inclined to ask for aid. And, for a lot of, antidepressants operate. Nonetheless, while specialists are quick to acknowledge the benefits – which can be lifestyle-saving – many express concern about our growing dependence.


“Prescription ranges have gone through the roof,” says Dr Matthijs Muijen, head of psychological health at WHO Europe. “On the demand side, men and women know antidepressants operate. I would even argue there is a degree of fashion about antidepressants. On the provide side, antidepressants have grow to be less expensive and more effortlessly obtainable. Doctors now know it’s effortless and ‘good’ to prescribe.”


Important to arguments around antidepressant use are inquiries about what constitutes “typical” sadness and in which the boundary lies among this and clinical depression. There is no reduce-and-dried response, and this ambivalence all around the use of antidepressants looks to be characteristic of these taking them. “It’s not excellent, but I just make use of the sources obtainable,” is a characteristic response.


Lisa Cunningham, 45, was signed off on sick leave and prescribed Prozac after suffering troubles at function. Quickly afterwards, she was attacked, leaving her with facial injuries and even deeper depression. For nearly eleven many years, Lisa remained on medicine, turning into steadily far more withdrawn, till she barely left the residence.


Cunningham’s story has a optimistic outcome: following being referred to a volunteering scheme by her GP she acquired involved in a gardening undertaking which led to a complete-time job. She then felt able to cease taking her medication. “Antidepressants did a essential occupation and I definitely feel I had clinical depression,” Cunningham says. “But I was a nervous, anxious kid.” She explains that whilst developing up, she was subjected to bodily aggression from men and women close to her, “so it was virtually inevitable I would get depression. Searching back, it would possibly have been far better if I’d had some sort of psychotherapy in college.”


For Darren Ellis, forty, lifestyle occasions and mental overall health have been similarly linked. Ellis lost his father at 16 and at the time was not presented any assistance. Ellis’s depression and anxiousness created and he was prescribed medicine right after medicine. None of the drugs worked and he twice attempted to take his personal daily life. It was only this year that he was in a position to get the one-to-1 cognitive-behavioural treatment (CBT) that, he says, is finally assisting him to recover.


Ellis believes items could have been diverse that the depression could have been prevented. “I’m certain I could have averted taking medication if I’d had therapy instantly,” he says. “I was confident – the life and soul of a celebration – till my dad died.”


The website link between life events and depression is of course not disputed, but it is of specific relevance now. A report by The Wellness and Social Care Information Centre exposed that in many places in the Uk – like Barnsley, Durham, Middlesbrough, Redcar, Salford and Sunderland – approximately one particular in six adults are prescribed antidepressants. By comparison, in affluent Kensington &amp Chelsea, it is one particular in 21.


Since the economic downturn started, Mind has reported a dramatic rise in the number of people calling its mobile phone line. “There are clear hyperlinks amongst unemployment and depression,” says Sophie Corlett, Mind’s director of external relations. “Following six months, one in 7 unemployed guys will create mental-health troubles. People are falling into debt and there’s a reciprocal partnership among debt and mental health.”


While virtually everybody with expertise of antidepressants reports locating them beneficial, numerous could have created use of option varieties of aid. “We know that folks go to the medical professional due to the fact they’re feeling reduced, and the reasons may possibly be domestic violence, debt, bereavement, marriage breakup, problems from past trauma,” says Corlett. “Some of these are practical and could have sensible solutions, whilst some are deep-rooted psychological concerns that need to have dealing with. Antidepressants are not often the response.”


For mild to moderate depression, unless of course it is persistent, the Nationwide Institute for Health and Care Excellence (Great) does not advise medication as a initial resort. Nonetheless, despite the government’s investment in the Improving Entry to Psychological Therapies programme, in some components of the nation individuals wait months for entry to CBT or equivalent treatment options. Likewise, it does not appear that people’s prescriptions are always reviewed each 6 months, as Wonderful suggests.


There are a lot of problems with prescribing antidepressants when there could be an alternative resolution. Antidepressants have side-results that we are only just discovering and, though rates have dropped as patents expire, the price to the NHS is nonetheless enormous.


It is unattainable to gauge whether we live in a much more nerve-racking age than that of our grandparents. What is specific is that attitudes and entry to drugs have changed. On stability, this is a very good issue. But as the economic system continues to flounder, the number of folks struggling with mental-wellness issues is most likely to boost, nearly undoubtedly top to the writing of nevertheless much more prescriptions.


“My worry is that we are medicalising all types of sadness in the belief that antidepressants are a risk-free drug that you just prescribe,” says Muijen.


Mind has named for precise study to be carried out into how several folks are taking antidepressants, how prolonged they get them for and whether they are getting any other treatment. It is a severe issue, Corlett says, that this data does not exist. Antidepressants are a vital instrument. But if, in several circumstances, we are just papering more than cracks, we should, as a society, face up to the depth of the problem.




Are we utilizing antidepressants to paper more than the cracks of a fractured society?

8 Nisan 2014 Salı

Circulation Retracts Paper By Stem Cell Pioneer And Its Personal Editor

Following an investigation by Harvard Health care School and Brigham and Women’s Hospital a 2012 paper published in Circulation has been retracted. The “institutional review… established that the data are sufficiently compromised that a retraction is warranted.” The two senior authors of the paper are Piero Anversa, a pioneering researcher in cardiac stem cells, and Joseph Loscalzo, the editor-in-chief of Circulation and the chairman of the division of medication at the Brigham.


As reported earlier on Retraction Observe, the paper has been cited thirty times according to Thomson Scientific’s Net of Knowledge.


Right here is the retraction statement:



For the write-up by Jan Kajstura, Marcello Rota, Donato Cappetta, Barbara Ogórek, Christian Arranto, Yingnan Bai, João Ferreira Martins, Sergio Signore, Fumihiro Sanada, Alex Matsuda, James Kostyla, Maria-Virginia Caballero, Claudia Fiorini, David A. D’Alessandro, Robert E. Michler, Federica del Monte, Toru Hosoda, Mark A. Perrella, Annarosa Leri, Bruce A. Buchholz, Joseph Loscalzo, and Piero Anversa (Cardiomyogenesis in the aging and failing human heart. Circulation. 2012126:18691881 DOI: 10.1161/CIRCULATIONAHA.112.118380), an ongoing institutional evaluation by Harvard Healthcare College and Brigham and Women’s Hospital has established that the data are sufficiently compromised that a retraction is warranted.


The American Heart Association American Heart Association, as a result, retracts the write-up.



A 2011 weblog on Nature.com thorough some of the events in a prolonged-standing controversy in excess of Anversa’s research.



Circulation Retracts Paper By Stem Cell Pioneer And Its Personal Editor

29 Mart 2014 Cumartesi

Regardless of Stimulus Dollars, Hundreds Of Hospitals Still Use Mostly Paper Data

About 6 % of U.S. hospitals have however to convert even the most basic ancillary solutions of laboratory, pharmacy and radiology to electronic health care record systems in spite of billions of bucks in money accessible to these services, wellness data executives said at the Association of Overall health Care Journalists yearly meeting.


An executive from the Healthcare Info and Management Methods Society advised journalists meeting this weekend in Denver that about 6 % of far more than 5,400 hospitals in the health info trade group’s HIMSS analytics database nonetheless aren’t at the first stage of the group’s 7-stage “electronic medical record adoption model.” The most current report on the model is linked right here.


“We’re discovering that individuals (suppliers) not maturing have a tendency to be smaller sized organizations,” John Daniels, vice president of strategic relations for the Healthcare Information and Management Methods Society, a Chicago-based mostly trade association that tracks electronic health-related record adoption in the U.S. said these days for the duration of a panel discussion at the journalists’ meeting.


The update comes as millions of Americans are signing up for wellness care coverage below the Cost-effective Care Act and policymakers and insurance organizations are looking to the well being care market for far more expense-efficient methods to supply health-related care and several observers see the adoption of electronic health data as critical.


In 2009, President Obama signed into law the Wellness Info Technological innovation for Financial and Clinical Well being Act, as component of the so-known as “federal stimulus” legislation identified as the American Reinvestment and Recovery Act. The law supplies some $ 20 billion to get healthcare care companies to use electronic medical records.


Health care care companies also face penalties subsequent year underneath the law from the federal government in the type of lower Medicare payments if they are not satisfying particular criteria that display they are making use of electronic healthcare data in a meaningful way. Some of the 1st criteria hospitals have to meet incorporate factors like eliminating handwritten orders and providing individuals electronic copies of their healthcare records when they leave the facility.


However in spite of the money, smaller sized, largely rural hospitals are in the identical boat as the rest of the hospital business in that they are “squeezed” by government an personal insurers who spend them, stated Mary Anne Leach, chief data officer at Children’s Hospital Colorado.


Leach, Daniels and Dr. Christopher Alban, clinical data specialist at Epic Programs Corp., a more substantial vendor of electronic well being records for hospitals and medical professionals, have been component of a panel speaking on electronic health data.


The panelists said rural hospitals are presently struggling to make an operating profit and the price of this kind of methods is a challenge even with the stimulus dollars.


Nonetheless, the panelists mentioned the risk of penalties and reduction of income from Medicare has triggered more amenities to enter the digital age.


About 37 percent of hospitals are in the ultimate three phases of adoption and the precentage is speedily growing. From the third quarter of 2013 to the fourth quarter of 2014 alone, the percentage of hospitals at the last three stages of adoption rose across the board, in accordance to HIMSS Analytics. Virtually three percent of hospitals are in the HIMSS last stage and no longer use paper charts to deliver and control patient care.


At that final stage, “it’s nearly a paperless surroundings,” Daniels said. “It’s rather significantly a totally-baked EMR capability.”



Regardless of Stimulus Dollars, Hundreds Of Hospitals Still Use Mostly Paper Data

26 Şubat 2014 Çarşamba

New Paper Check Strips Support to Detect Cancer

MIT engineers have designed new, simple, and affordable paper check strips to detect cancer.  This most recent technological breakthrough is comparable to a pregnancy test.  By getting a urine sample, paper test strips can detect cancer inside minutes.


The approach of detecting cancer


Presently, cancer screening approaches, like mammograms and colonoscopies have been instrumental in strengthening a patient’s outcome when detected early nonetheless, they are expensive and unavailable in remote areas.  This new strategy of using paper test strips to detect cancer in a person can also assist in identifying infectious conditions.


Paper test strips will at first be utilized in high-threat populations that is, people who had family members with the disease, or people who had cancer and are in remission.


How the paper check strips function


The technique to diagnose if a patient has cancer functions by getting hundreds of synthetic biomarkers simply detected in a patient’s urine.  Nanoparticles interact with tumor proteins called protease and trigger the synthetic biomarkers.  Currently, healthcare experts use the existing strategy by injecting sufferers with nanoparticles and then have them urinate on the paper check strip.  Researchers are making the check a lot more appropriate by implanting the nanoparticle formation under a patient’s skin for lengthy-phrase monitoring.  Analyzing the outcomes requires the use of highly specialized instruments.  Unfortunately, creating nations and rural settings locate it challenging to acquire and use these substantial-price, specialized tools.


MIT professor and Howard Hughes Medical Institute investigator, Sangeeta Bhatia explains,



“When we invented this new class of synthetic biomarker, we utilised a highly specialized instrument to do the examination.  For the establishing world, we considered it would be thrilling to adapt it alternatively to a paper test that could be carried out on unprocessed samples in a rural setting, with no the require for any specialized tools.  The easy readout could even be transmitted to a remote caregiver by a image on a mobile cellphone.”



In accordance to Samuel Sia, associate professor of biological engineering at Columbia University,



“This is a clever and inspired technology to produce new exogenous compounds that can detect clinical problems with aberrant higher protease concentrations.  Extending this engineering to detection by strip exams is a massive leap forward in bringing its use to outpatient clinics and decentralized wellness settings.”



Go through a lot more of George Zapo’s articles or blog posts about public, worldwide, and environmental well being at his site: Healthier Habits.



New Paper Check Strips Support to Detect Cancer