Testing etiketine sahip kayıtlar gösteriliyor. Tüm kayıtları göster
Testing etiketine sahip kayıtlar gösteriliyor. Tüm kayıtları göster

21 Nisan 2017 Cuma

"Hopeless": how senior doctor described NHS maternity unit"s testing regime

A senior figure in an NHS trust’s maternity unit under investigation over avoidable baby deaths has admitted that some practices in the unit were “hopeless”.


Andrew Tapp, medical director of women and children’s services at Shrewsbury and Telford hospital NHS trust, said in an email to a GP: “I think there are real problems here.” The GP had raised concerns about the maternity’s unit’s communication of test results.


The emails, seen by the Guardian, were sent in May 2016. The GP says his concerns about the safety of patients persist, citing a recent incident he was involved in that could have risked the life of an unborn baby.


The renewed concerns about the unit come as it has emerged that NHS chiefs are now investigating the deaths of 15 babies and three mothers. Several deaths have already been judged to have been avoidable; some were allegedly caused by a failure to correctly monitor babies’ heartbeats or spot infections early.


A team is also reviewing 10 further cases where patients survived but suffered harm.


The GP’s emails express alarm about the maternity unit’s procedures for communicating medical test results, accusing some departments of having a “fax and forget” attitude.


He said that without explanation or context, it was difficult for GPs to understand why particular tests had been ordered, how to interpret the results and how follow up appropriately.


The GP, who has expertise in patient safety, said: “At best these issues are an irritation; at worst, it’s dangerous. There seems to be an inability to change and to learn from mistakes. The safety culture isn’t responsive.


“It has always been thus during the years I’ve been a GP here. The reason why I’m speaking out is because as a GMC-registered doctor I have a duty to speak up about this kind of thing. I believe that patients are at risk and that there’s a lack of effective learning about safety at the trust. My motivation is to protect patients and I’m frustrated that there has been little change over the years.”


A second GP working with the hospital trust shared his fears.“When we have concerns we have to keep asking about them again and again,” he said. “There’s a genuine concern about patients and staff. There are lessons to be learned here.”


The case cited by the first GP was of a vulnerable young pregnant woman who was tested for a group B streptococcus infection. He said there was a significant delay in the maternity unit communicating the positive result to her GP, and that some of the information had been “scribbled” and was unclear.


Any woman with this infection is at risk of passing it to her baby – with potentially life-threatening consequences – unless antibiotics are promptly administered.


Last week an inquest into the death of one-day-old Pippa Griffiths, who contracted the same infection at the same hospital trust, found that she could have survived if she had received better medical care.


A Care Quality Commission report in January 2015 found that the trust required improvement and that while staff were caring, they needed more feedback about incidents to learn from their mistakes.


Maternity services at Shrewsbury and Telford hospital NHS trust were strongly criticised by an inquiry commissioned by NHS England into the death in 2009 of a baby, Kate Stanton-Davies.


In the email exchanges with the GP, Tapp, writes: “I have just finished a clinic at the Ludlow community hospital and have found another raft of tests that are simply cc’d to GPs without information going to GPs. I was informed by the senior sec[retary] that the process of cc results to GPs as they arrive in the community hospitals has been in place for 30 years. Does this need to be unpicked as well!! I suspect so.”


Another email states: “([name redacted] can you check on this and ensure that we are informing patients of abnormal results). The place for you to contact for any discussion was not ticked ([name redacted] can you look into this matter).”


In response to an example given by the GP of a test result inadequately dealt with by the trust, Tapp said: “Hopeless. [name redacted] can you look into this matter. I am fairly stunned that any one would have just popped this result into the post without context. I am not sure where a result sent to Ms M Midwife would go but can you ensure an effective educational program for colleagues.”


He goes on to say: “There does seem to be a bit of disconnect of brain here … The previous context does not seem to have been taken into consideration.”


He also adds: “I think there are some real problems here but there are opportunities to improve.”


Dr Edwin Borman, medical director at the Shrewsbury and Telford hospital NHS trust, said: “Effective and high quality communication between medical colleagues in primary and secondary care is extremely important for safe patient care.”


He said the trust – which handles 4,700 deliveries a year – had created a working group of consultants and GPs to review standards of communication following a patient’s discharge and would “continue to monitor and evaluate process to ensure continual improvement”.


Medics employed by the trust are the focus of both internal and external inquiries and at least four midwives are being investigated by the Nursing & Midwifery Council, according to a report in the Mirror.


The trust’s chief executive has apologised to the families of babies who died and said the trust was cooperating fully with the NHS review. But he added that it was his “firm belief” that the trust provided safe care for mothers and babies.


The health secretary, Jeremy Hunt, ordered an investigation into the deaths of a number of babies at the trust after seven deaths were judged to have been avoidable and bereaved families and the local coroner criticised the quality and safety of maternity care.


Five of the deaths involved apparent failures by staff to correctly monitor a baby’s heartbeat. Borman said the rate of baby deaths was no worse than anywhere else in the NHS.



"Hopeless": how senior doctor described NHS maternity unit"s testing regime

14 Aralık 2016 Çarşamba

"Angelina Jolie effect" boosted genetic testing rates, study suggests

Angelina Jolie’s revelation that she underwent a double mastectomy to reduce her chances of developing breast cancer boosted rates of genetic testing among women, but might have failed to reach those most at risk, new research suggests.


In a 2013 article for the New York Times, Jolie explained her decision to undergo a double mastectomy after finding that she had a mutation in a gene known as BRCA1 that greatly increased her risk of breast and ovarian cancers.


.

“I am writing about it now because I hope that other women can benefit from my experience,” she wrote. “Cancer is still a word that strikes fear into people’s hearts, producing a deep sense of powerlessness. But today it is possible to find out through a blood test whether you are highly susceptible to breast and ovarian cancer, and then take action.” After surgery her risk of developing breast cancer in later life fell from 87% to 5%.


The actor’s decision to tell her story was welcomed by medical experts and campaigners worldwide. But did women heed Jolie’s call?


Writing in the British Medical Journal, Sunita Desai and Anupam Jena of Harvard Medical School describe how they sought to answer the question by scrutinising data on US health insurance claims from more than nine million women aged between 18 and 64 .


These revealed that in the 15 working days following Jolie’s article, daily rates of testing for harmful mutations in BRCA1 and BRCA2 genes rose by 64%, compared with the 15 working days before. After six months, average monthly testing rates were still 37% higher than in the four months before the article’s publication.


But the study also reveals that while genetic testing rates increased, there was no change in average, overall mastectomy rates in the six months following the article’s publication – and showed a slight drop in mastectomy rates among those who had BRCA tests.


“The fact that mastectomy rates dropped after Angelina Jolie’s editorial suggests that that denominator of women who started getting the BRCA test became less appropriate for the BRCA test because they had a lower pre-test probability of having the mutation in the first place,” said Desai.


However, Douglas Easton, professor of genetic epidemiology at the University of Cambridge, noted that the study did not offer insights into the BRCA test results – meaning it was not possible to say whether women taking the test received negative results, or whether they had tested positive, but decided not to undergo surgery.


But Jennifer Litton, associate professor in the department of breast medical oncology at the University of Texas, said the results reflected what had been seen in clinics.


“The ‘Jolie effect’ was real, and we did have many more breast cancer patients ask about the test,” she said. “As only a small proportion of breast cancer patients harbour an abnormal gene, those that met national guidelines for testing had already had testing, so it did not change that group with the highest risk of a positive test.”


The research is not the first to explore the impact of Angelina Jolie’s declarations, although previous UK-based studies found that both testing among women at risk, and subsequent preventative surgery, increased.


A co-author of the UK-based research, Tony Howell, professor of medical oncology and director of scientific research at Prevent Breast Cancer, says the new US study looked at too short a period after publication of Jolie’s article to truly reflect its impact. “It takes weeks or months to get through the testing process in proper centres,” he said. “Same applies to risk-reducing breast surgery. This takes one to three years to filter through to surgery if all the checks and counselling are performed properly.”


Overall, says Howell, the 2013 article was valuable in raising awareness. “Jolie did a terrific job,” he said.



"Angelina Jolie effect" boosted genetic testing rates, study suggests

15 Kasım 2016 Salı

Testing sore throats at pharmacies won’t solve anything | Margaret McCartney

Are GPs to throw away the traditional box of wooden tongue depressors? People with sore throats are soon to be offered a new service – at the pharmacy. The NHS Innovation Accelerator, an organisation responsible for helping “with the adoption of promising new treatments and technologies”, has approved a new Sore Throat Test and Treat service that NHS England says is “evidence based and cost saving”.


My head is in my hands. This is neither evidence based nor shown to be cost effective, and may actually make pressure on the NHS worse.




Faced with a wait for to see a GP, it means effectively people will be able to access care faster if they pay for it




The pilot study – which occurred in Boots stores (whose head office analysed the data) – was not a randomised controlled trial. It showed it was possible for pharmacies to assess people with sore throats and use a “point of care” rapid antigen test to determine who should get antibiotics. This might sound superficially sensible. But the National Institute for Health and Care Excellence (Nice) does not recommend this rapid antigen test because it has a poor sensitivity for picking up relevant bugs.


It is already known – from randomised clinical trials – that this test does not help beyond normal care. Furthermore there has been no full cost-effectiveness analysis – let alone an independent cost-effectiveness analysis – of the Boots scheme. Without comparing the pilot to usual care, we have no way of knowing whether more or fewer antibiotics were prescribed. It is a travesty of evidence-based policymaking.


This scheme may actually increase demand on the NHS, fragmenting services but without improving care. More than half of the patients in the study said that if the pilot had not been available, they would have either have done nothing or treated themselves without assistance.This, if it held true, meant that antibiotics were subsequently used just because the scheme was there. Isn’t that good? Not necessarily.


The study concluded that if the pilot hadn’t been available then there could have been a “delay seeking medical treatment when it was needed”. But it didn’t show this, and not all bacterial throat infections need to be treated. In fact, antibiotics reduce the length of time of a sore throat by an average of 16 hours, with only a modest impact on complications such as ear infections. Balanced against common side-effects of antibiotics such as diarrhoea, as well as antibiotic resistance, there is often not a clear-cut reason to prescribe. This scheme expands the market for medicine, without clear benefits. Earlier is not always better. It gets worse.


In the pilot, patients paid £7.50 for the test and £10 for “antibiotics if required”. This is a clear subversion of the free at the point of use principle of the NHS. NHS England has not been able to tell me what the funding for the new service will be, where it will come from, or whether patients will still have to pay. Faced with a wait for a free appointment with a GP, it effectively means that people will be able to access care faster if they pay for it. Commissioners with stretched budgets may be content with that. But it should be absolutely resisted.


The relentless argument from rightwing thinktanks is that we need to charge for NHS appointments; and that the funding deficit in the NHS is so acute that all options should be on the table. But it is a dreadful argument. People who are poor have the biggest risk of earlier death and earlier disease. The very principle of the NHS – based on need, not ability to pay – subverts the otherwise natural course of allowing better healthcare to be only in the domain of the already better off.


This scheme isn’t the kind of change we need in the NHS. Sir Bruce Keogh, NHS England’s medical director, has said of it “innovation is not an option but a necessity if we are to built a sustainable NHS”. But “innovation” should not be an excuse for policymaking that isn’t evidence-based. There are far better ways to ensure that the NHS is sustainable.


The NHS does need more money. But it also needs to stop wasting money and effort on inadequately tested – or proven to be non-cost effective – but popular political policies. Take the health checks scheme or dementia screenings, for example – known to be ineffective and even harmful, through causing false positive diagnosis and over-treatment. Millions have been needlessly wasted that should have spent on useful care.


Similarly, there are multiple pressures on general practice that have been generated by appalling but avoidable political policy. The current benefits system is associated with worsening people’s mental health and has created an enormous amount of bureaucracy for GPs, which reduces the availability of appointments. And that is even before we get to the money and time spent administering to the competition and commissioning of the Health and Social Care Act, without evidence of gains for patients.


We are in the midst of an NHS financial crisis. If we want it to survive, we need real innovation. That means the bravery to stand up for evidence-based policymaking, and ensure that NHS policy always considers harms, and aims to reduce waste – and health inequalities.



Testing sore throats at pharmacies won’t solve anything | Margaret McCartney

13 Ekim 2016 Perşembe

Genetic testing should not be used to diagnose coeliac disease, experts say

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NPS MedicineWise’s new health guidelines also recommend considering surveillance rather than radiation to manage some low-risk cancers


Doctors should not routinely screen for herpes when testing for sexually transmitted infections, genetic testing should not be used to diagnose coeliac disease in most cases and radiation to treat some low-risk cancers should be reconsidered.


These are among the latest recommendations released on Thursday by NPS MedicineWise, an Australian-based organisation led by medical experts to provide doctors and patients with independent, evidence-based information.


Related: Could a diet tailored to your DNA save your life?


Related: Genetics tests flawed and inaccurate, say Dutch scientists


Continue reading…



Genetic testing should not be used to diagnose coeliac disease, experts say

13 Eylül 2016 Salı

Tories testing the electoral boundaries | Letters

The constituency boundary review was indeed independent (Editorial, 13 September) but it was based on the December 2015 electoral register at the government’s behest, contrary to the Electoral Commission’s recommendation of December 2016.
Jeremy Beecham
Labour, House of Lords


Why are the proposed boundaries based on the electoral register rather than population? The MP represents – and works for – all their constituents, not just those registered to vote.
Rosie Boughton
London


Geraint Davies (Letters, 12 September) compares The Archers’ listening figures of 5 million to the UK population of 65 million. Let’s compare the attendance at Premier League matches last weekend (354,071) with the population of England and Wales (53 million). Why does the media pay so much attention to football when the vast majority of us are not bothered?
Chris Andrews
Waterlooville, Hampshire


How can you write about leaders’ illnesses (Fit for office?, G2, 13 September) and fail to mention Sir Anthony Eden’s gall bladder problems during the Suez crisis?
Dr Sally Cheseldine
Balerno, Edinburgh


Our wonderful NHS offers a free pneumonia vaccination to all over 65 (Clinton campaign voices regret at hiding pneumonia, 13 September).
Jenny Moir
Chelmsford, Essex


When did a Bullingdon boy ever stay to clear up the damage he created (Cameron quits but denies he is snubbing May, 13 September)?
Gren Gaskell
Malvern, Worcestershire


Pedantry rules OK in linguistics, and beyond the ken of Guardian typography. “Guantánamo” has a written accent (Letters, 12 September), but “Guantanamera” has none, as stressed (predictably) on the “me”. If you don’t believe it, just listen to the song. There are rules for these things, quite elegant ones, but this might take us beyond A-level to degree-level linguistics.
Nicholas Ostler
Hungerford, Berkshire


Join the debate – email guardian.letters@theguardian.com



Tories testing the electoral boundaries | Letters

22 Ağustos 2016 Pazartesi

Wen Hair Care baldness suit signals need for toxin testing in beauty products

Last week brought news that Wen Hair Care, a celebrity endorsed “sulfate-free” shampoo and conditioner line is preparing a $ 26.5m settlement after a class action lawsuit over thousands of complaints of hair loss and skin rashes.


While cases like Wen put people on high alert, it is difficult to steer clear of potentially toxic products. Every day the average person uses nine personal care products, according to a survey by the Environmental Working Group. With most personal product ingredient lists taking up an unpronounceable paragraph, it can be a daunting area for consumers to navigate. Especially when something like the Wen lawsuit provides a reminder that personal care products are barely regulated in the US.


There currently is no independent testing of ingredients in beauty products. However, if a particular cosmetic product is causing serious health issues, the Food and Drug Administration (FDA) will step in with a consumer warning, as was the case with Wen. The FDA issued a public warning last month, saying that the company failed to address safety concerns. Wen, however, has persisted in saying that its products are safe, despite the FDA’s objections and the company’s own decision to settle the class action suit.


In a statement, the FDA said that it could do little else to compel the company: “We do not have the legal authority to require a cosmetics firm to provide product safety information.”


The only FDA regulation of the cosmetic industry dates back to a few rules adopted in 1938 that have remained largely unchanged, leaving the cosmetic industry effectively self regulating. That self regulation allows cosmetic companies to voluntarily report adverse effects from their products to the FDA.


In Wen’s case, 127 instances of adverse effects were reported to the FDA, a fraction of the around 21,000 complaints made to the company.


While cosmetic ingredients have not changed dramatically in the past 50 years, various additives in personal care products have received scrutiny in recent years. When there is a lot of attention around a cosmetic ingredient, companies will sometimes look to replace it with an alternative to avoid controversy. That can create new issues, as replacement ingredients have often been studied less than what they’re designed to supplant.


In the case of Wen, its products were advertised specifically as not having sulfates or detergents, as there have been public objections to their safety.


The FDA doesn’t require full ingredients lists to be made public, so it is still unclear what chemicals might have prompted consumers’ hair loss, but it’s possible that one of the substitutes was the issue.


Another way the beauty industry has responded to a lot of the concerns around its ingredients is by marketing “natural” cosmetic and hair care lines. But because the term “natural” is not regulated, it doesn’t mean anything.


“Natural is a marketing trick to get people to pay more,” says Perry Romanowski, a cosmetic chemist and a co-founder of The Beauty Brains, a blog about the ingredients in cosmetics. “Cosmetics are not natural: there is nothing natural about them.”


New legislation might help address the regulatory gap. Democratic Senator Dianne Feinstein and Republican Senator Susan Collins have proposed legislation that would give the FDA the power to issue recalls and conduct their own safety tests of ingredients found in cosmetics.


A number of major cosmetic companies, such as Estée Lauder, have backed the bill, but it still faces opposition from the Independent Cosmetic Manufacturers and Distributors, the cosmetic trade group for small to mid-sized cosmetic companies.


While lobbyists fight it out in Washington, Nneka Leiba, deputy director of research at the Environmental Working Group, has a few words of advice for consumers. It’s best if you can use single-ingredient alternatives, says Leiba, but she allows that not everyone can use something like coconut oil for all their skincare needs. She says reducing the number of products used everyday or using products with fewer ingredients, like those without artificial fragrances, can be another strategy.


If a person is worried about the ingredients in their makeup, says Romanowski, not using products is another way to alleviate that worry. After all, he points out, there is “no health benefit in using cosmetics”.



Wen Hair Care baldness suit signals need for toxin testing in beauty products

7 Ağustos 2016 Pazar

Bowel cancer: 29% of UK hospitals not following guidance on testing younger patients

Almost 50 hospitals around the country are failing to provide crucial screening tests for younger people diagnosed with bowel cancer, according to a leading cancer research charity.


People under the age of 50 who are diagnosed with bowel cancer are not being tested for Lynch syndrome in 29% of hospitals around the country. Lynch syndrome is an inherited disorder, and testing for it helps detect those at greater risk of recurrence, helps inform treatment options, and identifies those with family members who may also be at risk of bowel cancer.


In 2014, the Royal College of Pathologists changed its guidance to make the testing of bowel cancer patients for Lynch syndrome mandatory after diagnosis. But research conducted by Bowel Cancer UK and the Royal College of Pathologists and released on Monday shows that this advice is not being followed.


Related: Processed meats rank alongside smoking as cancer causes – WHO


The percentage of hospitals that tested younger bowel cancer patients for Lynch syndrome varied across the UK. In Northern Ireland, 100% of hospitals that responded to a freedom of information request were conducting the screening. In Scotland, 93% of hospitals were offering the screening. This fell to 69% in England and just 29% in Wales.


Even in those hospitals that did carry out the test on younger patients, only 56% did so automatically, without prompting from the multi-disciplinary team, in accordance with the guidelines.


These numbers were an improvement on the first time such data was requested. In 2015, Bowel Cancer UK issued FOI requests to all hospitals across the UK and discovered that only 49% were testing patients under the age of 50 for the syndrome. This has increased to 71% in 2016.


Bowel cancer is the UK’s second biggest cancer killer and the fourth most common form of cancer. While most of those diagnosed with bowel cancer are over the age of 50, more than 2,400 people under 50 are found to have the condition each year, and there has been a 25% increase in the number of under-50s diagnosed with the disease in the past 10 years. Sixty per cent of people under the age of 50 diagnosed with bowel cancer are diagnosed in the later stages of the disease, when the chances of survival are lower.


Asha Kaur, policy manager at Bowel Cancer UK, urged hospitals to work together. “The guidelines have now been in place two years and there are still 40 hospitals in England alone not doing the test at all, plus a huge variation in approach to testing across the UK.”


Kaur urged those with a family history of Lynch syndrome or a family history of bowel cancer to go to their GPs and ask about testing for the disorder.



Bowel cancer: 29% of UK hospitals not following guidance on testing younger patients

24 Ağustos 2015 Pazartesi

Why Practice Fusion And Theranos Will Disrupt Lab Testing On Electronic Health Record Platforms

[unable to retrieve total-text articles]


Connectivity and integration are essential attributes which include value and increase the consumer knowledge when taking into consideration whether or not to adopt a specific electronic well being record (EHR) platform. While numerous sorts of EHRs can get the work completed, the path of least resistance to record, translate and integrate critical information defines a superior [...]


Why Practice Fusion And Theranos Will Disrupt Lab Testing On Electronic Health Record Platforms

9 Mayıs 2014 Cuma

Routine Shock Testing Not Necessary For the duration of ICD Implantation

When cardiologists implant defibrillators in sufferers at substantial risk of dying from a heart rhythm disorder they practically often execute a defibrillation check in which they induce a lethal arrhythmia, ventricular fibrillation, to make confident the gadget accurately detects the arrhythmia and terminates it with an acceptable shock. But program defibrillation testing has by no means been shown to be risk-free or required. In recent years some specialists have maintained that regimen defibrillation testing could not be required.


Now a new examine, presented yesterday at the Heart Rhythm Society meeting in San Francisco, offers proof that even though schedule testing is usually secure it could improve problems with out generating any improvement in outcomes.


In the Simple (Shockless Implant Evaluation) trial, sponsored by Boston Scientific and led by researchers at McMaster University in Hamilton, Ontario, two,500 patients in 18 countries undergoing ICD implantation have been randomized to routine defibrillation testing (DT) or no DT.


Soon after 3 years of followup there was no substantial difference in the major endpoint of the trial, which was the fee of death due to arrhythmia or the failure of a first shock to terminate a lethal arrhythmia (seven.2% in the no-DT arm versus 8.3%  in the DT arm, hazard ratio .86 CI .65-1.14,  non-inferiority p&lt0.001). There was no difference amongst the groups in complete mortality.


The authors concluded that defibrillation testing “does not enhance ICD shock efficacy or decrease mortality.” Despite the fact that regimen testing is “generally reduced risk,” problems may possibly sometimes get area. Since of these information, “the ‘no testing’ strategy to regimen ICD implantation should be preferred.”


“This is the very first time the connection between defibrillator testing and patient outcome has been studied independently in a randomized setting and with these results, we can confidently say that defibrillator testing, though protected, is not required at the time of ICD implantation,” explained the lead writer of the examine, Jeff Healey, in a press release. “These final results ought to alter physician practice and could aid reduce expenses without having compromising patient outcomes.”



Routine Shock Testing Not Necessary For the duration of ICD Implantation

5 Nisan 2014 Cumartesi

Can a New Novel Conserve the Whales Against Navy’s Sonar Testing

Sonar Testing and Harm to Whales and Dolphins


There’s an previous adage that the surroundings is never saved — just continually being saved. And the U.S. Navy’s testing and training with higher-intensity lively sonar is a ideal illustration.


When it comes to the next 5 many years of instruction and testing routines in Southern California and Hawaii, the Navy’s not just up to its previous tricks, it’s moving forward with actions that, by its very own estimate, will inflict an 11 fold increase over the harm the Navy estimated for its last 5 many years of training. The National Marine Fisheries Support — the company charged with defending whales and dolphins — has authorized practically 9.6 million situations of temporary hearing loss and considerable disruptions of crucial conduct, thousands of long term injuries, and more than a hundred deaths. (Huffington Submit, one/27/14)


Can a Novel make an effect?


Go through a book that depicts the impact on our planet that this kind of testing has on marine daily life and daily life on the planet prior to it gets a major motion image (film rights have presently been sold).  I just finished reading through this brilliant novel, The Emissary, by Patricia Cori. The story is propelled from page 1 by many seemingly unrelated occurrences. Inside minutes of each and every other, 3 events take spot about the globe. In Los Angeles, hundreds of blackbirds drop out of the sky, zapped to their death, mid-flight. Concurrently, on the East Coast, in Maine, residents awaken to discover miles of beach covered in tens of 1000′s of dead fish. And in New Zealand, 150 whales and dolphins lay dead or dying, like gigantic boulders thrown from the ocean, on a resort seashore. Overhead, a unusual grid-like pattern in the clouds hangs reduced and menacing, in excess of the desperate scene.


The Emissary packs a scrumptious journey filled with intrigue and strategies and whisks you off on a trip that you don’t want to get off. Via the story that unfolds it also invites all of us to search at the part we perform in our evolving world. By way of the fast-paced occasions that occur, deftly led by our heroine Jamie Hastings, readers are guided to turn into emissaries as well—sent on a really particular mission that is born from author Patricia Cori’s passion in the world. That mission for some may possibly be to curl up in a chair, to give themselves a respite from life’s demands, and get lost in the voyage of The Emissary. For other people, the unique mission turns into a journey of self-exploration, of appreciation of all creatures fantastic and little, and an invitation to completely embrace our roles as ambassadors of our planet. It is a story of hope, commitment, and perseverance. But far more, it is a story of love amongst a very specific female and those who generate the songs in our waters. May we use the messages contained within The Emissary to help us ensure people songs proceed forever.” —Christine Andrew, Enlightening Radio


The Emissary, a Novel by Patricia Cori Just launched on March 2014.


 About the Writer


She’s been known as a “real existence Indiana Jones” and a living model of the adventurous spirit and seeker within us all. Internationally acclaimed writer Patricia Cori is one particular of the most effectively-recognized and established authorities on the realms of the mystic. In 2012, she founded the international nonprofit association Save Earth’s Oceans, Inc., committed to restoring the stability of our fragile ocean ecosystems and conserving the whales and dolphins from whaling, slaughter, and exploitation.


We have naturally reached a point where we cannot basically turn a blind eye to what is happening to our oceans.  If only the dolphins and whales could communicate to us about what we have accomplished to them in their habitat.   I felt like this guide does a great occupation of currently being that voice and helping each and every of us to wake up and recognize it is our duty to become conscious and involved in this battle.


Healthier Blessings,


Sandy


Get your copy of newly released The Emissary right here.  Pass it on and let’s help increase awareness and hopefully obtain far more traction for this battle.


Visit our Healthier Residing Website



Can a New Novel Conserve the Whales Against Navy’s Sonar Testing

10 Mart 2014 Pazartesi

Fukushima~ 3 Years, No Transparent Food Testing

This coming week will mark three many years given that the ongoing Fukushima Daiichi nuclear meltdowns began. It’s also been  one year since Fukushima Fallout Awareness Network or FFAN filed a legal document known as a Citizen Petition with the US Foods and Drug Administration to reduce the existing allowable amounts of Cesium 134 and 137 in food, nutritional dietary supplements and pharmaceuticals.


The Worldwide Physicians for the Prevention of Nuclear War (IPPNW) in Germany wrote a report requesting a almost identical reduce in radiation permitted in foods as FFAN’s petition, so clearly an international motion is forming on this vital concern.  The USFDA has responded that they need a lot more time to consider FFAN’s Citizen petition, but one year is long ample won’t you agree?  The predicament is urgent and we need to have your help while the comment period is still open or FDA might reject the petition entirely.  A new Youtube of the campaign is up now, please consider a look and network widely: http://www.youtube.com/channel/UCsv-C0GvUOv9OrO5wZuVWUQ.  Our MoveOn “Bye Bye Becquerels” companion petition is part of this crucial campaign and featured on the video as properly, and can also be located at www.FFAN.us

We’ve seen a modest increase in media coverage but Fukushima is still not receiving virtually sufficient, specially taking into consideration that the situation becomes much more critical every day. This past week Pacifica Radio’s Venture Censored produced a great program with updates on numerous fronts:  the USS Reagan lawsuit, an skilled overview of the realities of Fukushima, and the influence on our meals and health.  FFAN’s Marybeth Brangan is one particular of the guests, so please take a pay attention and network this important broadcast:  http://www.kpfa.org/archive/id/100729.

And last but not least, It is been 1 year considering that my book “Silence Deafening, Fukushima Fallout..A Mother’s Response” was published as a second edition and is obtainable in print and epub formats at  http://www.SilenceDeafening.com.  Fukushima’s affect on our lives has been mind-boggling at instances, and it’s been tough to discover stability.  But I tend toward optimism and following 3 years have identified the way back to wellness coaching and holistic nutrition  ~ with the major focus on detoxification ~ at http://www.NewHealthDesign.com.

Get care, get action, and maintain the faith!


Kim   


Kimberly Roberson


Director, Fukushima Fallout Awareness Network



Fukushima~ 3 Years, No Transparent Food Testing

EdTech, Student Privacy, As well A lot Testing? Q&A With The Department Of Education

Jordan: I have to inquire a question about video games. I’m a big fan of game-based mostly learning. I’ve observed, just watching my personal children, how strong video games can be as an instructional strategy. Obviously, video games are not the magic resolution to every little thing, but they are a single powerful tool that teachers can commence to add to their toolboxes. But there are a good deal of barriers to classroom implementation. The most significant barrier has to do with resources and access to technology. But even in colleges where assets are not in the way of adopting game-based mostly studying answers, there’s usually inadequate specialist advancement for teachers. Or, in schools that do have ample technological resources, teachers discover that college students don’t have ample entry to engineering at property to make introducing game primarily based studying profitable.


What other obstacles to implementing game primarily based studying or educational technologies do you see? And how does the Division of Training perform a element in eliminating those obstacles?


Shelton: I as well am a large fan of properly-designed studying video games as one particular of many resources for understanding and teaching. I consider there are 3 other huge barriers to broad adoption in classrooms. The initial is the hardest – the cultural stigma that men and women have to get in excess of that taking part in a game is wasting time.


The 2nd is that in addition to education for teachers on how to integrate game based mostly understanding we need to have much more and better resources that make game integration less complicated and much more seamless and make the information a lot more accessible. We have to make it less difficult and more beneficial for teachers to embed video games in their instructional toolkit and every day routines.


Ultimately, with a couple of notable exceptions, educational games as a group want to be greater developed and clearer about what they are excellent for and what they are not developed to do. While educational games utility is unclear, teachers are generating a rational choice to invest their time in other strategies. But when a case can be created that the games will make a difference, I consider items will open up pretty swiftly. An innovator named Zoran Popovic worked with a effectively-created studying game to integrate adapative algorithms to improve its efficiency. They then partnered with schools and districts to launch Algebra Challenges that resulted in college students from many backgrounds solving literally millions of algebra issues and mastering crucial ideas.


The far more examples we have like that the a lot more speedily we’ll see broad adoption of learning video games in classrooms.


Jordan: The recent buzzwords in training are plentiful: teacher accountability, formative and substantive assessment, the widespread core, data-driven instruction, 1-to-a single technology adoption, character training. I’ve been an outspoken critic of these buzzwords, arguing that they obfuscate the concerns a lot more than they open a room for genuine conversation. In distinct, I’ve written extensively about the issues with buzzwords like “grit, perseverance, and optimism.” Lucky for us, the conversation about education is often evolving. The words we hear these days will be replaced with new words.


I’m curious how you feel the conversation will adjust in the many years to come? Which buzzwords will drift away and which will become more predominant? And in the political sphere, what educational problems will have a principal place in the 2016 presidential election season?


Shelton: I have no concept what the next round of buzzwords will be, and whilst some of the terms like grit, persistence and resilience have become faddish, there is critical science and a fair quantity of common sense behind them.



EdTech, Student Privacy, As well A lot Testing? Q&A With The Department Of Education

3 Mart 2014 Pazartesi

China Cracks Down on DNA Testing

Genetic testing has grown to be a organization huge adequate in China to warrant the government’s intervention. Early in February, the government quietly put the brakes on the provision of genetic tests to buyers by domestic hospitals and a variety of medical and health institutions.


If the ban persists it could blunt the ambitions of Shenzhen-based mostly BGI, which has the world’s greatest gene-sequencing capability, and its various competitors, such as Beijing-based Berry Genomics, Hunan-based 2nd Xiangya Hospital of Central South University, and Shenzhen-listed DAAN Gene. (For much more on BGI’s history and businesses, see this Forbes Asia magazine story). BGI itself is in the approach of getting ready for an IPO to list element of its business.


BGI declined to comment on how the ban would have an effect on its organization. It is understood the organization is in the process of searching for government approval for the commercial use of its items, such as its proprietary sequencing application and the Comprehensive Genomics-branded products created by the American organization it acquired a 12 months ago. An approval would permit it to sell its noninvasive DNA test, invented in 2010, which screens a fetus for Down syndrome by testing the mother’s blood.


The ban has created the country’s regulation of genetic testing – which existed till now in a legal grey location – between the most stringent, going beyond the U.S. Meals and Drug Administration’s latest action in stopping a U.S. company, 23andMe, from giving health-connected genetic exams right to shoppers.


The authorities seem to be most concerned about DNA-based mostly prenatal testing. Even although the government is comforting its notorious population controls to cope with an aging population, many Chinese dad and mom still have only one youngster, and want to make sure its overall health if not its intercourse and other traits. Now providers of genetic exams, with some exceptions, will have to apply for particular permission from government companies to perform such tests.


BGI President Wang Jian

BGI President Wang Jian



Prenatal testing is the most common in the nascent company of genetic testing in China. A Chinese securities analyst estimates its market to be well worth 50 billion yuan ($ eight billion) a year, primarily based on the quantity of expected births and a testing charge of 3000 yuan ($ 480) every single. A much more sensible figure may be about 480 million yuan (US$ 77 million), the amount invested by the 160,000 girls who have taken the exams given that they were created offered in China. In the United States, the comparable marketplace is estimated to be well worth upward of $ one.3 billion a 12 months.


The official ban was produced by means of a cross-company announcement posted on the web site of the China Food and Drug Administration. The vague wording of the announcement can make it unclear how extensively it would apply to distinct types of genetic testing, but it names prenatal DNA exams as an illustration of those subject to the ban. It applies to all existing tasks except people accredited by the government, and requires all connected medical units to be licensed by the government before they can be produced, imported, offered or employed, possibly covering the world’s most popular gene-sequencing equipment, made by Boston-primarily based Illumina, Inc.


From now on, clinical applications of gene-sequencing technologies can be supplied only at locations accredited as pilot trial points by the National Wellness and Arranging Commission, the Chinese population handle authority. And they have to be accomplished according to rules, with “proper certifications and evaluations.”


Other than that, a blanket ban is enforced. “Before related certification and rules are promulgated, health-related institutions cannot carry out clinical applications of gene sequencing. These ongoing projects have to stop right away,” the announcement states.


In the announcement the government raises its concerns about the rapidly improvement of genetic testing as it has moved from labs to clinical applications. “Many genetic testing products and technologies, these for prenatal testing integrated, belong to the fields of pioneering study studies. They pose troubles in issues this kind of as ethics, privacy, the safety of human heredity assets, biological security, as properly as the management of diagnosis skills of relevant healthcare institutions, their pricing policy and quality controls,” it states in a extended run-on sentence.


Before the ban, Chinese overall health clinics had supplied consumers a proliferation of genetic tests for the diagnosis of different diseases, from tumors and diabetes to immunity system deficiency and hearing impairment. In Shenzhen, in which BGI has its headquarters, a key newspaper estimated the ban on prenatal testing would result in the birth of some eleven,000 infants with congenital problems, based on a total of 210,000 infants born final 12 months in the city and a nationwide birth defect fee of 5.six%.


Earlier, Chinese newspapers reported that BGI’s DNA-based prenatal testing for Down syndrome was getting censured by the government soon after an anonymous letter accused it of employing testing gear that was not certified by the government. The products in query, ironically, is the industry’s most sophisticated model, Hiseq2000, made by Illumina.



China Cracks Down on DNA Testing

2 Mart 2014 Pazar

Pfizer Commences Testing For Over-The-Counter Lipitor

Hunting backward to improve its long term, Pfizer will as soon as yet again consider to gain FDA approval to market its blockbuster drug, atorvastatin (Lipitor), over-the-counter (OTC). Peter Loftus reviews in the Wall Street Journal that the company has commenced a clinical research to assistance the application for minimal-dose atorvastatin (10 mg).


Over-the-counter statins have been unsuccessfully proposed in the past. Merck attempted many occasions to gain approval for lovastatin (Mevacor). In 2007 an FDA advisory panel recommended against approval. And in 2011, prior to the expiration of Pfizer’s patent on Lipitor, the firm explained that it would pursue OTC approval.


The new examine, which has been registered on ClinicalTrials.Gov, will enroll 1200 folks at pharmacies in the US. The main outcome of the research will be to establish the percentage of individuals who comply with instructions on the box to verify their LDL levels and who consider suitable actions based on the test end result. “It’s our responsibility to show individuals can securely and efficiently use these goods,” a Pfizer executive told the WSJ.


But the examine may supply an response to a query that is no longer being asked. New lipid tips launched last 12 months are primarily based on an overall assessment of chance and do not hinge on lipid measurements. The report estimates guideline co-author Neil Stone: “The new recommendations insist on a patient-clinician discussion before a statin prescription is written.”


But, Loftus writes, “other medical doctors say the elimination of distinct cholesterol targets could make it easier for individuals to consider an OTC statin. Once individuals know they are in a chance group identified by the new guidelines—for which the lower-dose level in in excess of-the-counter Lipitor is appropriate—they could get the product off the shelf and not fret about treating to a particular target.”


The WSJ reports that after peaking at virtually $ 13 billion in 2006, Lipitor sales for Pfizer final yr had been $ two.three billion. An OTC model could bring in an addition $ one billion in sales every single 12 months, Goldman Sachs estimates.



Pfizer Commences Testing For Over-The-Counter Lipitor

28 Ocak 2014 Salı

Twenty Years In the past These days, The California Supreme Court Upheld Mandatory Drug Testing In University Sports activities

Twenty many years in the past nowadays, the California Supreme Court ruled in Hill v. NCAA that the NCAA’s necessary drug testing program complied with the privacy requirements in the California state constitution.


This selection reversed a lower court ruling that forbid the NCAA from requiring pupil-athletes at California schools from submitting to mandatory drug testing.


The original challenge to the NCAA’s drug testing plan was filed in 1990 by a linebacker on the Stanford football staff and the co-captain of the Stanford women’s soccer crew.  The two student-athletes argued that the NCAA drug testing demands violated Report I, Segment one of the California Constitution, which granted all California citizens a constitutional proper to privacy.



English: Logo of Stanford University

Stanford University in the end intervened in the Hill litigation on behalf of its pupil-athletes.




Stanford University in the long run intervened in the situation and argued on behalf of its student-athletes’ rights.  And each the California Superior Court and the California Court of Appeal agreed with their position — discovering the NCAA drug testing system illegal underneath California state law.


However, when the California Supreme Court reviewed the situation, it reached the opposite conclusion.


In accordance to the California Supreme Court, pupil-athletes have a diminished expectation of privacy because they already “undergo frequent physical examinations, reveal their body and health care situations to coaches and trainers, and often dress and undress in same-intercourse locker rooms.”


The court also concluded that the NCAA has ”legitimate regulatory objectives in conducting testing for proscribed drugs,” which are based on the two student-athlete security and sustaining the sanctity of college competition.


Nowadays, the NCAA continues to enforce its rigid drug testing protocol even although several facets of the NCAA’s arguments Hill seem to be to conflict with the NCAA’s a lot more recent legal positions.


Most notably, in Hill, the NCAA argued a special duty in “protecting the wellness and security of student athletes.”  By contrast, in a latest wrongful death litigation stemming from a university football player’s repeated concussions, the NCAA denied any legal duty to protect the well being and safety of student-athletes.


________________________________


Marc Edelman is an Associate Professor of Law at the City University of New York‘s Baruch School, Zicklin College of Company, exactly where he has published more than 25 law review “articles on sports law matters, such as “A Brief Treatise on Amateurism and Antitrust Law” and “The Long term of Amateurism following Antitrust Scrutiny.”


Comply with me on Twitter right here



Twenty Years In the past These days, The California Supreme Court Upheld Mandatory Drug Testing In University Sports activities

24 Ocak 2014 Cuma

Pharmaceutical Testing : How Does This Influence You?

Pharmaceutical Testing


Soon after years of investigation and advancement, medicines sold in the United States must nonetheless pass the official approval process of the Food and Drug Administration (FDA). Medicines are not able to be sold in the United States right up until the FDA has sanctioned their sale. The FDA will approve or deny a drug based on its personal study and will also offer you recommendations for risk-free prescription and use of the medication.


Interestingly, the FDA does not carry out testing on its personal. Drug companies are accountable for testing the drugs, and the FDA makes use of results from these organizations to make a determination on approval. The scientists at the FDA who are concerned in the research incorporate pharmacologists, chemists, doctors, and statisticians.


The FDA Drug Approval Approach


The process used by the FDA to approve medicines usually requires a number of months, and significantly of the weight is positioned on the pharmaceutical firm to test the drug. The phases required to get a drug to its approval stage incorporate the following:


Pre-Clinical: the pharmaceutical company develops the drug, conducts animal tissue slice testing, and then submits a form to the FDA referred to as an “Investigational New Drug” application (IND).




  • Clinical phase &amp trials: Comprised of three phases, which each and every expand in dimension, the pharmaceutical company conducts human trials to determine side effects, to see no matter whether it works in humans, and to recognize the suitable dosage.


  • NDA Overview: The drug is submitted to the FDA below a “New Drug Application,” which covers inspections of the manufacturing facility, drug labeling meetings, and a formal request to approve the drug.


  • Publish-Marketing: After drug approval the FDA will proceed to monitor the drug’s performance with a program named “MedWatch.” This post-approval program assists the FDA to consider swift action if a drug is found to be unsafe.


Controversy at the FDA


The FDA has not been immune to controversy and testing methods utilised by the company have been routinely questioned by researchers. A recent analysis by the Yale University School of Medication criticized the distinctions in approval processes used for diverse drugs. One of the strategies disapproved of by Yale researchers was the inequality of clinical trials.


Some drugs authorized by the agency necessary just a single trial prior to approval was granted even though other drugs reached approval only soon after a number of large-scale clinical trials. Although the FDA has offered motives for the variations in approval methods, the Yale evaluation remained essential of the overall process for pharmaceutical testing.


Potential for Expedited Approval


The recent meningitis scares at numerous American universities has brought to light problems of foreign medications and the barriers people medicines need to pass ahead of they may be sold and employed in the United States. At the time of the 1st outbreak on the East Coast, the Centers for Ailment Manage and Prevention (CDC) had to make a specific request of the FDA for a European drug to be allowed for use in the United States to prevent the spread of the deadly ailment.


Even though the FDA agreed to approve the drug for use in the United States, there were limitations connected to the importation of the drug. Princeton, the place the outbreak started, was permitted just enough doses to preserve its student population protected. In light of the unsafe outbreak, the FDA’s approval approach has been criticized anew by medical professionals who have suggested that an accelerated approval process is required.


Cammie Channing is a dental hygienist and wellness author from Tucson, Arizona. She has written articles or blog posts about dentistry, skincare, basic well being, and considerably a lot more.



Pharmaceutical Testing : How Does This Influence You?